Certified Hospice and Palliative Assistant (CHPNA) Practice Test 2025 – All-in-One Study Resource for Exam Success!

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What does the term 'tolerance' signify in the context of drug exposure?

Increased sensitivity to a drug

Absence of drug effects

Diminution of drug effects over time

In the context of drug exposure, 'tolerance' refers to the phenomenon where the body becomes accustomed to a drug over time, leading to a reduction in its effects. This means that individuals may require higher doses of the drug to achieve the same therapeutic effect that was experienced initially. Tolerance develops due to various physiological adaptations, including changes in drug metabolism or alterations in receptor sensitivity.

Understanding tolerance is crucial in the context of palliative and hospice care because it can significantly affect pain management and the effectiveness of medications used to alleviate symptoms. Therefore, recognizing and addressing tolerance is important for ensuring optimal patient care, as healthcare providers may need to adjust dosages or consider alternative therapies to maintain efficacy.

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Improved drug efficacy

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